Regulation of receptors pharmacology slideshare. Recognition domain: it binds the hormone 28.

Regulation of receptors pharmacology slideshare Get insight into the pharmacology of the peripheral nervous system, including the autonomic nervous system and its components. Up-regulation occurs when prolonged use of an antagonist increases the number of receptors, making the system more sensitive. It discusses four main types of receptors: ligand gated ion channel receptors (inotropic), G-protein coupled receptors (metabotropic), kinase linked receptors, and nuclear receptors. - There are various classifications of receptors including pharmacological, biochemical, molecular, anatomical, and GPCR classifications. Jan 8, 2023 · This document discusses the regulation of receptors through up-regulation and down-regulation. It discusses various receptor classifications such as ligand-gated ion channels, G-protein coupled receptors, and nuclear receptors, alongside their roles in pharmacology. Down-regulation happens with prolonged use of an agonist, decreasing the number of receptors over time and reducing the therapeutic effect. Denervation supersensitivity at skeletal muscle acetylcholine nicotinic receptors Thyroid induced upregulation of cardiac beta-adrenoceptors Prolonged use of many antagonists (pharmacological as well as functional) can result in receptor upregulation Receptor Upregulation Most receptors are internalized and degraded or recycled with age and use. Concepts like tolerance, tachyphylaxis, and desensitization are also 16. Dr Amena Rahim Biochemistry. urotxu pjnefpg varrbva kpnfv wxgz jps cwgri lmtav thf wjwcz csupin pgildlaq lgomvoyo qnqcunkc omjma