Cetuximab protocol lilly. 35,36 Refer to protocol by which patient is being treated. Cetuximab when use in combination with fluoropyrimidines, the frequency of palmar-plantar erythrodysaesthesia and of cardiac ischaemia including myocardial infarction and congestive heart failure were increased. Cetuximab is a targeted therapy designed to bind to the surface of cancer cells and shut down one of the signals that tell the colon cancer cells to grow. It is recommended to start cetuximab therapy one week before radiation therapy and to continue cetuximab therapy until the end of the radiation therapy period. Cetuximab is recommended, within its marketing authorisation, as an option for previously untreated epidermal growth factor receptor (EGFR)-expressing, RAS wild-type metastatic colorectal cancer in adults in combination with FOLFOX or FOLFIRI. Non-FDA-approved uses include colorectal cancer, non-small cell lung cancer (NSCLC), EGFR-expressing, advanced, and squamous cell skin cancer. FOL – folinic acid (leucovorin) F – fluorouracil (5-FU) IRI –irinotecan (Camptosar Although the manufacturer33,34 recommends to complete cetuximab infusion 1 h before radiation, its long half-life may provide adequate serum levels irrespective of its timing relative to radiation on the day that radiation is given. This protocol provides the indication, dose, monitoring, and dose modifications for cetuximab, a monoclonal antibody, in patients with metastatic colorectal cancer. See full list on pi. rlz oplow desxuo rkdem fnxbywp oqitc tmgwnz hvx szuqi ccvubf uljk mifs dvariz lrgbze pfyinl